UK-Swindon: Cytometers.
Section I: Contracting Authority
I.1) Name and addresses
UK Research & Innovation
Polaris House, Swindon, SN2 1FL, United Kingdom
Tel. +44 7593602434, Email: mrcprocurement@ukri.org
Contact: Procurement Manager - MRC LMB
Main Address: www.ukri.org
NUTS Code: UKH12
I.2) Joint procurement
The contract involves joint procurement: No.
In the case of joint procurement involving different countries, state applicable national procurement law: Not provided
The contract is awarded by a central purchasing body: Yes.
I.3) Communication
The procurement documents are available for unrestricted and full direct access, free of charge, at: https://www.delta-esourcing.com/tenders/UK-UK-Swindon:-Cytometers./TB67EP83TB
Additional information can be obtained from: the abovementioned address
Tenders or requests to participate must be sent electronically via https://www.delta-esourcing.com/tenders/UK-UK-Swindon:-Cytometers./TB67EP83TB to the abovementioned address
Electronic communication requires the use of tools and devices that are not generally available. Unrestricted and full direct access to these tools and devices is possible, free of charge, at: Not provided
I.4) Type of the contracting authority
Body governed by public law
I.5) Main activity
Health

Section II: Object
II.1) Scope of the procurement
II.1.1) Title: UKRI-2399 High Specification Flow Cytometer Cell Sorter (minimum 6 lasers)
Reference Number: Not provided
II.1.2) Main CPV Code:
38434510 - Cytometers.

II.1.3) Type of contract: SUPPLIES
II.1.4) Short description: The LMB Flow Cytometry Unit wish to purchase a high specification, high throughput flow cytometer cell sorter with a minimum of 6 spatially separated lasers and a minimum of 30 fluorescence channels that is housed under a certified Class II biocontainment hood. The flow cytometer cell sorter should provide increased resolution and flexibility to sort a wide range of particles, bacteria and cell types (both primary and cultured) in various formats including 4 way or 6-way sorting, and in 96 and 384 well formats.

The goal is to provide a communal cell sorter to support research in areas of artificial biology requiring chromosome sorting for the rewriting of the human genome. Customizable options in nozzle size and pressure settings will allow purification of sensitive cell types such as neurons and single-cell organoid suspensions, facilitating downstream functional experimentation.
II.1.5) Estimated total value:
Value excluding VAT: 608,000
Currency: GBP
II.1.6) Information about lots:
This contract is divided into lots: No

II.2) Description

II.2.2) Additional CPV codes:
Not Provided
II.2.3) Place of performance:
UKH12 Cambridgeshire CC

II.2.4) Description of procurement: The LMB Flow Cytometry Unit intend to purchase and install a high specification flow cytometer cell sorter, equipped with a high throughput plate sorting option, housed under a certified Class II microbiological safety hood and operating a minimum of 6 different wavelength spatially separated lasers in order to perform purification and fractionation of various cell types and particles utilising a broad range of fluorescent markers.

Objectives

1.The cell sorter should be equipped with 6 high-powered, spatially separated lasers with the following excitation wavelengths and powers; 349-355nm (100mW), 405nm (100mW), 445nm (100mW), 488nm (100mW), 561nm (100mW), 637-640nm (100mW).
2.The cell sorter should be housed under a certified Class II biocontainment system.
3.The cell sorter should be outfitted with a fluorescence unmixing and/or compensation algorithm to separate and correct for spectral overlap of individual signatures of highly overlapping fluorochromes or fluorescent proteins.
4.The cell sorter should be capable of achieving a signal processing rate of 70,000 events per second (eps) for analysis and the ability to sort particles at high purity (≥99%) at flow rates ≥20,000 particles per second.
5.The cell sorter should be able to detect and distinguish small particles from noise using the side scatter detector (SSC) as low as 200nm.
6.The cell sorter should be outfitted with a high-throughput plate option, capable of sorting single cells/particles in a wide range of plate formats including customized, 6, 12, 24, 96, and 384 well.
7.The cell sorter should be upgradable to include additional lasers such as 375nm, 532nm, 594nm, 795-808nm.
8.The cell sorter should come equipped with a temperature control option for both the sample input and collection device from 4-42oC.

Maintenance contract (parts and labour) should be detailed in years 3, 4 and 5 after successful installation following expiry of the requested 2-year warranty period.
II.2.5) Award criteria:
Criteria below
Quality criterion - Name: Conformance to the specification / Weighting: 55
Quality criterion - Name: Social Value Model / Weighting: 10
Quality criterion - Name: Warranty / Weighting: 5
Quality criterion - Name: Seventh Laser offering / Weighting: 10

Cost criterion - Name: Price / Weighting: 20

II.2.6) Estimated value:
Value excluding VAT: 603,000
Currency: GBP
II.2.7) Duration of the contract, framework agreement or dynamic purchasing system:
Start: 23/01/2023 / End: 23/01/2024
This contract is subject to renewal: No
Description of renewals: Not provided

II.2.10) Information about variants:
Variants will be accepted: No
II.2.11) Information about options:
Options: No
Description of options: Not provided
II.2.12) Information about electronic catalogues:
Tenders must be presented in the form of electronic catalogues or include an electronic catalogue: No
II.2.13) Information about European Union funds:
The procurement is related to a project and/or programme financed by European Union funds: No
Identification of the project: Not provided
II.2.14) Additional information: To respond to this opportunity please click here: https://ukri.delta-esourcing.com/respond/TB67EP83TB


Section III: Legal, Economic, Financial And Technical Information
III.1) Conditions for participation
III.1.1) Suitability to pursue the professional activity, including requirements relating to enrolment on professional or trade registers
List and brief description of conditions:
Not Provided
III.1.2) Economic and financial standing
Selection criteria as stated in the procurement documents
List and brief description of selection criteria:
Not Provided
Minimum level(s) of standards possibly required (if applicable) :
Not Provided
III.1.3) Technical and professional ability
Selection criteria as stated in the procurement documents
List and brief description of selection criteria:
Not Provided
Minimum level(s) of standards possibly required (if applicable) :
Not Provided
III.1.5) Information about reserved contracts (if applicable)
The contract is reserved to sheltered workshops and economic operators aiming at the social and professional integration of disabled or disadvantaged persons: No
The execution of the contract is restricted to the framework of sheltered employment programmes: No

III.2) Conditions related to the contract

III.2.2) Contract performance conditions
Not Provided
III.2.3) Information about staff responsible for the performance of the contract
Obligation to indicate the names and professional qualifications of the staff assigned to performing the contract: No

Section IV: Procedure
IV.1) Description OPEN
IV.1.1) Type of procedure: Open

IV.1.3) Information about a framework agreement or a dynamic purchasing system
The procurement involves the establishment of a framework agreement - NO
In the case of framework agreements justification for any duration exceeding 4 years: Not Provided


IV.1.6) Information about electronic auction:
An electronic auction will be used: No
Additional information about electronic auction: Not provided
IV.1.8) Information about the Government Procurement Agreement (GPA)
The procurement is covered by the Government Procurement Agreement: Yes
IV.2) Administrative information
IV.2.1) Previous publication concerning this procedure:
Notice number in the OJ S: Not provided
IV.2.2) Time limit for receipt of tenders or requests to participate
Date: 16/12/2022 Time: 15:00

IV.2.4) Languages in which tenders or requests to participate may be submitted: English,
IV.2.6) Minimum time frame during which the tenderer must maintain the tender: Not Provided
IV.2.7) Conditions for opening of tenders:
Date: 16/12/2022
Time: 15:00


Section VI: Complementary Information
VI.1) Information about recurrence
This is a recurrent procurement: No
Estimated timing for further notices to be published: Not provided
VI.2) Information about electronic workflows
Electronic ordering will be used No
Electronic invoicing will be accepted Yes
Electronic payment will be used No
VI.3) Additional Information: The contracting authority considers that this contract may be suitable for economic operators that are small or medium enterprises (SMEs). However, any selection of tenderers will be based solely on the criteria set out for the procurement.
For more information about this opportunity, please visit the Delta eSourcing portal at:
https://ukri.delta-esourcing.com/tenders/UK-UK-Swindon:-Cytometers./TB67EP83TB

To respond to this opportunity, please click here:
https://ukri.delta-esourcing.com/respond/TB67EP83TB
VI.4) Procedures for review
VI.4.1) Review body:
UK Research and Innovation
Polaris House, Swindon, SN2 1FL, United Kingdom
Tel. +44 7593602434, Email: mrcprocurement@ukri.org
Internet address: www.ukri.org
VI.4.2) Body responsible for mediation procedures:
Not provided
VI.4.3) Review procedure
Precise information on deadline(s) for review procedures:
Not Provided
VI.4.4) Service from which information about the lodging of appeals may be obtained:
Not provided
VI.5) Date Of Dispatch Of This Notice: 16/11/2022

Annex A